Job Title: Director, Accounting

Department: Finance

Location: Menlo Park, US

LOCATION: Position will be on-site in Menlo Park, CA or Princeton, NJ

About Summit:

Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD-1 and VEGF.

Summit has begun its clinical development of ivonescimab in non-small cell lung cancer (NSCLC), with three active Phase III trials:

• HARMONi is a Phase III clinical trial which intends to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who have progressed after treatment with a 3rd generation EGFR TKI (e.g., osimertinib).

• HARMONi-3 is a Phase III clinical trial which is designed to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

• HARMONi-7 is a Phase III clinical trial which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC whose tumors have high PD-L1 expression.

Ivonescimab is an investigational therapy that is not approved by any regulatory authority in Summit’s license territories, including the United States and Europe. Ivonescimab was approved for marketing authorization in China in May 2024. Ivonescimab was granted Fast Track designation by the US Food & Drug Administration (FDA) for the HARMONi clinical trial setting.

Overview of Role:

The Director of Accounting will manage the accounting process including R&D accruals, payroll, and accounts payable. This individual will also support financial audits and contribute to strategic process improvements. Other responsibilities will apply as needs of the business change.

Role and Responsibilities:

• Oversee R&D accruals including contract manufacturing accrual, clinical trials related accruals, accounts payable and payroll
• Maintain internal and operational controls necessary to monitor performance and comply with SOX 404, as required
• Ensure completeness and accuracy of month-end close tasks; is accountable for overseeing journal entries, balance sheet reconciliations, financial flux, internal controls and management reporting
• Act as primary liaison with external auditors; prepare and coordinate all appropriate material for quarterly reviews and annual audits
• Assist with compilation of information for preparation of tax compliance items, including but not limited to annual provisions/returns and other tax-related items and review the external tax advisors’ deliverables.
• Provide leadership and mentorship to accounting team members, fostering a high-performance and collaborative culture
• Partner cross-functionally with departments across the organization and support strategic business initiatives with sound financial insights
• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

• Bachelor’s or master’s in accounting; CPA preferred
• 10+ years of progressive experience in public and private accounting
• Experience in the biotech or life science industry is strongly preferred
• Thorough knowledge of US GAAP principles
• Deep understanding of clinical trial accruals and contract manufacturing finance is a significant advantage
• Demonstrated ability to operate in a fast-paced environment.
• Leadership ability, with a track record of building and motivating high-performing teams
• Exceptional writing, communication, interpersonal & presentation skills
• Attention to detail, accuracy, and confidentiality
• Excellent organizational, management, analytical and decision-making skills
• An ability to work well cross functionally and across geographies
• Impeccable integrity and a strong work ethic

The pay range for this role is $184,000-$230,000 annually. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.