Investigator Sponsored Trial Opportunities

Summit Therapeutics (“Summit”) may provide support for independent research such as Investigator Sponsored Trials (“ISTs”) that advance medical and scientific knowledge about Summit products, related therapeutic areas, or disease state areas of interest.

An IST is a study that is designed, implemented, and sponsored by an investigator / entity / group who has requested monetary funding and / or Summit materials (e.g., drug) to support the execution of a research study. ISTs include a variety of clinical studies such as interventional and non-interventional studies, as well as prospective or retrospective studies. Other types of studies that may be considered as an IST include non-clinical (animal), in-vitro and in-vivo studies. Summit may not serve as the sponsor of an IST.

Qualified researchers / investigators are requested to submit their proposals according to the instructions found on this page. Proposals are reviewed by a cross-functional Summit Scientific Review Committee that meets periodically. Summit’s decision to support a proposal will be based on its research merit and alignment with our Areas of Scientific Interest. Furthermore, Summit will also consider the expertise of the proposed sponsor, including their experience in the relevant therapeutic area, demonstrated ability to successfully conduct clinical trials, and available resources.

Summit does not provide operational support (e.g., authorship of a protocol, statistical analysis, study report, publication, site monitoring) for ISTs. Operational support for ISTs is the responsibility of the sponsor.

Please be aware that funding is limited, and submission of an application (even one that meets stated criteria) does not guarantee that funding will be granted to your organization. Summit receives many applications for support and cannot support them all.​

Summit will reassess the areas of interest in 2024 for future IST submissions. For any questions, please email us at​