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and Associated Disease Susceptibility

The Microbiome is Critical to Health1,2 Trillions of microbes in the human gut Changes in the delicate balance of the microbiome can cause dysbiosis

Changes in diversity (dysbiosis) associated with disease susceptibility3

And in some cases, like cancer, may limit effective therapeutic outcomes

“Now is the time to refocus microbiota research…and advance research on the mechanisms that underly the causal links between the human microbiota and infectious and immune-mediated diseases”

Giovanni, Schneider, Calder, Fauci

Refocusing Human Microbiota Research in Infectious and Immune-mediated Diseases: Advancing to the Next Stage. The Journal of Infectious Diseases, Volume 224, Issue 1, 1 July 2021, Pages 5–8

1.   Hafnagl K, et al. Seminars in Immunopathology 2020, 42 75-93 https://link.springer.com/article/10.1007/s00281-019-00775-y

2.   Buford TW. Microbiome 2017, 5(1) 80 https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-017-0296-0

3.   Giovanni, Schneider, Calder, Fauci. Refocusing Human Microbiota Research in Infectious and Immune-mediated Diseases: Advancing to the Next Stage.

     The Journal of Infectious Diseases, Volume 224, Issue 1, 1 July 2021, Pages 5–8